PUBLICATIONS

2019

Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function.

McNair LF, Andersen JV, Aldana B, Hohnholt MC, Nissen JD, Sun Y, Fischer KD, Sonnewald U, Nyberg N, Webster SC, Kapur K, Rimmele TS, Barone I, Hawks-Mayer H, Lipton JO, Hodgson NW, Aoki CJ, Rosenberg PA, Waagepetersen HS.

Journal of Neuroscience 2019 Mar 29. pii: 0894-18. doi: 10.1523/JNEUROSCI.0894-18.2019. [Epub ahead of print]

PMID: 30926746

Mechanisms of sleep and circadian ontogeny through the lens of neurodevelopmental disorders.

Barone I, Hawks-Mayer H, Lipton JO.

Neurobiol Learn Mem. 2019 Jan 19. pii: S1074-7427(19)30011-5. doi: 10.1016/j.nlm.2019.01.011. [Epub ahead of print]

PMID: 30668981

2018

Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups.

Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Pierre-François J, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA, Mesirov JP, Pomeroy SL, Fraenkel E.

Cancer Cell. 2018 Sep 10;34(3):396-410.e8. doi: 10.1016/j.ccell.2018.08.004.

PMID: 30205044

2017

mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex

Kelly, E, Schaeffer, SM, Dhamne, SC, Lipton JO, Lindemann, L, Honer, M, Jaeschke, G, Super, CE, Lammers, SH, Modi, ME, Silverman, JL, Dreier, JR, Kwiatkowski, DJ, Rotenberg, A, Sahin, M.

Neuropsychopharmacology. 2017 Dec 5. doi: 10.1038/npp.2017.295.

PMID: 29206810

 

Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy

Lipton JO*, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M. (*co-corresponding author)

Cell Reports. 2017 Jul 25;20(4):868-880.   doi: 10.1016/j.celrep.2017.07.008.

PMID: 28746872

Neural Circuitry of Wakefulness and Sleep.

Scammell TE, Arrigoni E, and Lipton JO.

Neuron. 2017       Feb 22;93(4):747-765.    doi: 10.1016/j.neuron.2017.01.014.

PMID: 28231463

2016

Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex

Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Reports. 2016 Oct 18;17(4):1053-1070. doi: 10.1016/j.celrep.2016.09.054.

PMID: 27760312

2015

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.

Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Güttler T, Davis F, Asara JM, Sahin M.

Cell. 2015   May 21; 161(5):1138-51.      doi: 10.1016/j.cell.2015.04.002.    

PMID: 25981667

2014

The Neurology of mTOR.

Lipton JO and Sahin M.

Neuron. 2014     Oct 22;84(2):275-91.      doi: 10.1016/j.neuron.2014.09.034.

PMID: 25374355