mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex

Kelly, E, Schaeffer, SM, Dhamne, SC, Lipton JO, Lindemann, L, Honer, M, Jaeschke, G, Super, CE, Lammers, SH, Modi, ME, Silverman, JL, Dreier, JR, Kwiatkowski, DJ, Rotenberg, A, Sahin, M.

Neuropsychopharmacology. 2017 Dec 5. doi: 10.1038/npp.2017.295.

PMID: 29206810

 

Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy

Lipton JO*, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M. (*co-corresponding author)

Cell Reports. 2017 Jul 25;20(4):868-880.   doi: 10.1016/j.celrep.2017.07.008.

PMID: 28746872

                                                                              *****

Neural Circuitry of Wakefulness and Sleep.

Scammel TE, Arrigoni E, and Lipton JO.

Neuron. 2017       Feb 22;93(4):747-765.    doi: 10.1016/j.neuron.2017.01.014.

PMID: 28231463

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Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex

Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Reports. 2016 Oct 18;17(4):1053-1070. doi: 10.1016/j.celrep.2016.09.054.

PMID: 27760312

                                                                              *****

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.

Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Güttler T, Davis F, Asara JM, Sahin M.

Cell. 2015   May 21; 161(5):1138-51.      doi: 10.1016/j.cell.2015.04.002.    

PMID: 25981667

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The Neurology of mTOR.

Lipton JO and Sahin M.

Neuron. 2014     Oct 22;84(2):275-91.      doi: 10.1016/j.neuron.2014.09.034.

PMID: 25374355